منابع مشابه
Atheroma: links with antiphospholipid antibodies, Hughes syndrome and lupus.
Antiphospholipid antibodies (aPL) are found in a variety of autoimmune diseases, and are thought to predispose to arterial and venous thrombosis. These antibodies, when investigated in different assays in vitro, activate endothelial cells and promote uptake of modified LDL to macrophages. These observations suggest that aPL can contribute to atheroma development by targeting some of the sequent...
متن کاملEthnic and geographical variation in antiphospholipid (Hughes) syndrome.
Investigation of the clinical epidemiology of the antiphospholipid syndrome (APS) is in its early stages. During the past 20 years, studies of antiphospholipid antibodies (aPL) and APS have been made in many countries and ethno-geographical groups. aPL appear to occur in all populations studied, with some variations noted in their frequency and in the clinical complications. Environmental and g...
متن کاملAntiphospholipid (Hughes) syndrome: beyond pregnancy morbidity and thrombosis
The antiphospholipid syndrome is an autoimmune disease characterised by recurrent arterial or venous thrombosis, pregnancy morbidity and the persistence of positive antiphospholipid antibodies. Many other clinical manifestations may occur including heart valve disease, livedo reticularis, thrombocytopenia and neurological manifestations such as migraine and seizures. We review a number of other...
متن کاملRenal artery stenosis in the antiphospholipid (Hughes) syndrome and hypertension.
BACKGROUND Hypertension is common in the antiphospholipid (Hughes) syndrome (APS) and its cause is poorly understood. Anecdotal evidence suggests that renal artery stenosis (RAS) may be a relevant and treatable cause of hypertension. OBJECTIVE To investigate the prevalence of RAS in patients with APS and hypertension. PATIENTS AND METHODS Three groups of patients were evaluated: (1) 77 pati...
متن کاملUnexpected Coronary Thrombosis Induced by Antiphospholipid Syndrome (hughes Syndrome): Case Report
UNEXPECTED CORONARY THROMBOSIS INDUCED BY ANTIPHOSPHOLIPID SYNDROME (HUGHES SYNDROME) CASE REPORT (Abstract): Antiphospholipid syndrome (APS), one of the most common states of acquired hypercoagulability, is diagnosed by the persistent presence of antiphospholipid antibodies and recurrent episodes of vascular thrombosis. We present the case of a 39-year-old man late-presenting for cardiac rehab...
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ژورنال
عنوان ژورنال: Hamdan Medical Journal
سال: 2018
ISSN: 2227-2437
DOI: 10.4103/hmj.hmj_83_18